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Saturday, April 10, 2010

Low-Cost Automation of Sputum Smear Analysis by Imaging Cytometry------Pavak shah

Smear Microscopy Advantages: Low Cost

Low-Cost imaging: low-magnification; LED excitation; CMOS camera sensor; fixed focus, fixed-stage; Smear analysis automation

Advantages: Low-cost; potential high sensitivity

Image Analysis: many possibilities, simplest approach: segment image by intensity threshold; more sophisticated strategy: shape space classifier

Why imaging cytometry?
low-cost, low-power; portable, easily ruggedized, temperature stable reagents, increses testing throughput.

Continued and future development: software- image analysis optimization

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